Article

Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants

2020-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Genotype-first approach allows to systematically identify carriers of pathogenic variants in BRCA1 / 2 genes conferring a high risk of familial breast and ovarian cancer. Participants of the Estonian biobank have expressed support for the disclosure of clinically significant findings. With an Estonian biobank cohort, we applied a genotype-first approach, contacted carriers and offered return of r...

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Literature Corpus work: 086c915a-901a-5235-8906-c109dd69b41b
DOI: 10.1101/2020.06.29.20139691

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Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participantsDOI 10.1101/2020.06.29.20139691Read

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