Article

Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability

2019-07-18

Abstract excerpt

Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic disorders. Mutational burden has been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and autism. The rate of mutation is a fundamental genomic parameter and direct estimates of this parameter have been enabled by accurate comparisons of whole-genome sequences between parents and offspr...

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Literature Corpus work: 40e2d4df-496f-5824-8b53-7b142ac76817
DOI: 10.1101/706705

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