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Origins and Long-Term Patterns of Copy-Number Variation in Rhesus Macaques.

Molecular biology and evolution - 13 Apr 2021

Thomas Gregg W C, Wang Richard J, Nguyen Jelena, Alan Harris R, Raveendran Muthuswamy, Rogers Jeffrey, Hahn Matthew W

Abstract excerpt

Mutations play a key role in the development of disease in an individual and the evolution of traits within species. Recent work in humans and other primates has clarified the origins and patterns of single-nucleotide variants, showing that most arise in the father's germline during spermatogenesis. It remains unknown whether larger mutations, such as deletions and duplications of hundreds or thousands of...

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PMID: 33226085
DOI: 10.1093/molbev/msaa303
PMCID: PMC8042740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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