Article

Genetic evidence for a periplasmic protein as a component for a subset of NtrYX two-component systems

2025-11-07

Abstract excerpt

PlrSR, a member of the NtrYX family of two-component regulatory systems (TCSs), is required for the classical bordetellae, including the causative agent of whooping cough, Bordetella pertussis , to persist in the lower respiratory tract. The plrSR genes are in the middle of a six-gene cluster whose regulation and roles during infection were unknown. rsmB and plrP are often found 5’ to plrSR homologs in β- and...

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Literature Corpus work: 40da89ce-7ef3-54b7-9529-a1d1c4a90db3
DOI: 10.1101/2025.11.07.687182

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