Article
Phosphorylated CpxR restricts production of the RovA global regulator in Yersinia pseudotuberculosis.
PloS one - 1 Jan 2011
Liu Junfa, Obi Ikenna R, Thanikkal Edvin J, Kieselbach Thomas, Francis Matthew S
Abstract excerpt
BACKGROUND: RovA is a global transcriptional regulator of gene expression in pathogenic Yersinia. RovA levels are kept in check by a sophisticated layering of distinct transcriptional and post-transcriptional regulatory mechanisms. In the enteropathogen Y. pseudotuberculosis, we have previously reported that the extracytoplasmic stress sensing CpxA-CpxR two-component regulatory system modulates rovA expression....
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