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Programmed DNA elimination was present in the last common ancestor of <i>Caenorhabditis</i> nematodes

2025-10-24

Abstract excerpt

In most organisms, all cells inherit the same genome, and many mechanisms exist to preserve its integrity across cell divisions. Programmed DNA elimination (PDE), the targeted removal of specific genomic regions from somatic cell lineages during early embryogenesis, is a striking exception. Since its discovery in parasitic nematodes over a century ago, PDE has been observed in diverse eukaryotes, including ciliate...

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Literature Corpus work
40bee107-30fb-5dad-8af0-1e9063c6aadc
DOI
10.1101/2025.10.23.681605
Open publication

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Programmed DNA elimination was present in the last common ancestor of <i>Caenorhabditis</i> nematodesDOI 10.1101/2025.10.23.681605
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