Article

Argonautes and small RNAs associated with nematode programmed DNA elimination

2025-10-23

Abstract excerpt

Programmed DNA elimination (PDE) selectively removes portions of the genome during development, deviating from the genome constancy rule. Our understanding of PDE mechanisms, including the involvement of small RNAs and transposases, is mainly based on studies in the single-cell ciliates, whereas in metazoans, the PDE mechanisms remain largely unknown. In the parasitic nematode Ascaris , PDE removes and remodels a...

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Literature Corpus work: 2c4c8ac7-ed40-5a33-abb0-80dbfc681096
DOI: 10.1101/2025.10.23.684123

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