Article
A sequence motif for DNA double-strand break and telomere healing during programmed DNA elimination
2026-03-09
Abstract excerpt
Programmed DNA Elimination (PDE) is an exception to the paradigm of genome integrity, removing selected DNA sequences during development. PDE is observed in dozens of metazoan species from diverse phyla, but its molecular mechanisms and biological significance in most metazoa remain largely unknown. During PDE in the nematode Oscheius tipulae , DNA double-strand breaks (DSBs) are generated at subtelomeric regions...
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Identifiers and source
- Literature Corpus work
- 0c62571b-c5cd-55e2-9e03-4f48df4ee13a
- DOI
- 10.64898/2026.03.06.709695