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Therapeutic Advances for Huntington’s Disease

12 Jan 2020

Abstract excerpt

Huntington’s disease (HD) is a progressive neurological disease that is inherited in an autosomal fashion. The cause of disease pathology is an expansion of cytosine-adenine-guanine (CAG) repeats within the huntingtin gene (HTT) on chromosome 4 (4p16.3), which codes the huntingtin protein (mHTT). The common symptoms of HD include motor and cognitive impairment of psychiatric functions. Patients exhibit a...

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PMID: 31940909
DOI: 10.3390/brainsci10010043

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