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Article

Mitochondria defects are involved in lead-acetate-induced adult hematopoietic stem cell decline.

Toxicology letters - 19 May 2015

Liu Jun, Jia Dao-Yong, Cai Shi-Zhong, Li Cheng-Peng, Zhang Meng-Si, Zhang Yan-Yan, Yan Chong-Huai, Wang Ya-Ping

Abstract excerpt

Occupational high-grade lead exposure has been reduced in recent decades as a result of increased regulation. However, environmental lead exposure remains widespread, and is associated with severe toxicity implicated in human diseases. We performed oral intragastric administration of various dose lead acetate to adult Sprague Dawley rats to define the role of lead exposure in hematopoietic stem cells (HSCs)...

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Identifiers

PMID: 25800560
DOI: 10.1016/j.toxlet.2015.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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