Article

Amino Terminal Recognition by a CCR6 Chemokine Receptor Antibody Blocks CCL20 Signaling and IL-17 Expression via β-arrestin

2021-02-11

Abstract excerpt

<h4>Background: </h4> CCR6 chemokine receptor is an important target in inflammatory diseases. Th17 cells express CCR6 and a number of inflammatory cytokines, including IL-17 and IL-22, which are involved in the propagation of inflammatory immune responses. CCR6 antagonist would be a potential treatment for inflammatory diseases such as psoriasis or rheumatoid arthritis. The aim of this study is to develop an anta...

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Literature Corpus work: 407b6ef1-4e93-54b9-9c89-eef12e4b20a4
DOI: 10.21203/rs.3.rs-183666/v1

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