Article

The Super Elongation Complex (SEC) in development and disease

2013-01-01

Abstract excerpt

Chromosomal translocations involving the <i>mixed lineage leukemia (MLL)</i> gene are associated with infant acute leukemia. There are a large number of translocation partners of MLL that share very little sequence similarities, yet their translocations into MLL result in the pathogenesis of leukemia. To define the molecular reason why these translocations result in leukemogenesis, I purified several of the common...

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Literature Corpus work: 4060eb21-1a76-526a-aaf2-96d2ca7209c5
DOI: 10.21954/ou.ro.0000f0ae

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