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A comparison of the effects of an Ascophyllum nodosum ethanol extract and its molecular weight fractions on the inflammatory immune gene expression in-vitro and ex-vivo

2016-10-01

Abstract excerpt

The anti-inflammatory bioactivities of three crude extracts of Ascophyllum nodosum (cold water, hot water and 80% ethanol extract (EE)) were initially evaluated. Following from this, the immune modulatory efficacy of EE and its MW fractions (<3.5, 3.5–100, >100kDa) were compared. In TNF-α challenged Caco-2 cells, the crude extracts reduced IL-8 production (P<0.001), while the EE caused a >2 fold down-regulation of...

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Literature Corpus work
1794b93d-9277-5ed0-98a4-772c95d3415e
DOI
10.1016/j.ifset.2016.07.027
Open publication

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