Article

Three‑Dimensional Immune Cartography Uncovers Subclinical Remodeling in Psoriasis

2025-10-23

Abstract excerpt

<title>Abstract</title> <p> Psoriasis is characterized by a complex immune micro-environment, yet most spatial studies rely on two-dimensional (2D) immunohistochemistry (IHC) histology. We investigated whether routine immunohistochemistry coupled with three-dimensional (3D) digital reconstruction can provide quantitative insight into immune-epithelial architecture across the psoriatic spectrum. Skin biopsies fro...

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Literature Corpus work: 4047fc84-0e8a-5f8f-9bc6-740a8c4de778
DOI: 10.21203/rs.3.rs-7581947/v1

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