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UXT-V1 contributes to the malignant phenotypes of colorectal cancer via GSK3β by activating Wnt/β-catenin pathway

2023-01-25

Abstract excerpt

<h4>Background: </h4> Colorectal cancer (CRC) is one of malignant tumors that seriously threatening human health. β-catenin is a central hub in Wnt pathway, aberrant activation of Wnt/β-catenin signaling pathway promotes the tumorigenesis/progression of CRC. <h4>Methods and Results: </h4> Here we found a β-catenin interactor, UXT-V1, could modulate Wnt signaling. The expression of UXT-V1 mRNA was increased in CRC...

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Literature Corpus work
402f80e0-efb0-58d1-b3bc-6de85bded09f
DOI
10.21203/rs.3.rs-2392726/v1
Open publication

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