Behavioral and Steroidogenic Pharmacology of Phenyl Ring Substituted Etomidate Analogs in Rats

Abstract excerpt

<title>Abstract</title> <p>Background: Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids and associated with significant morbidity. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce side effects that limit dosing, efficacy, and patient tolerability. Among the most potent inhibitors is the general a...

Topics

Open a Topic to create a Post that cites this publication.

• Adrenal Cortex Hormones
• Animals, Genetically Modified
• Hemodynamics
• Hypnotics and Sedatives
• Mutation
• Receptors, Adrenergic
• Receptors, GABA-A
• Steroids

Identifiers and source

Literature Corpus work

401cb8c3-52e3-5feb-b21d-1a546e5c7cfa

DOI

10.21203/rs.2.10854/v2