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Article

Sperm-Derived Dysfunction of Human Embryos: Molecular Mechanisms and Clinical Resolution

2025-05-29

Abstract excerpt

Apart from the male genome, the fertilizing spermatozoon delivers to the oocyte several factors that are needed for embryonic development and whose deficiency can cause human embryo dysfunction. Sperm oocyte-activating factor, identified as phoshoplipase C zeta (PLCζ), drives oocyte exit from meiotic arrest and preparation for the first mitotic division by a signaling pathway initiated by periodic rises of free cy...

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Literature Corpus work
3fe08cd6-8ab4-53c2-a506-9736f1f6ba59
DOI
10.20944/preprints202505.2353.v1
Open publication

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Sperm-Derived Dysfunction of Human Embryos: Molecular Mechanisms and Clinical ResolutionDOI 10.20944/preprints202505.2353.v1
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