Article

Membrane-tethered peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as allosteric biased ligands

2020-11-24

Abstract excerpt

Over the last decade, the urotensinergic system has garnered significant attention as a promising new target for the treatment of various cardiovascular diseases and also cancer. Significant investment toward the development of clinically relevant UT ligands for therapeutic intervention has been made but have met little to no success to date. The UT system, which has yet to be effectively targeted, therefore remai...

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Literature Corpus work: 3fdc4199-1749-5077-8041-6b5ec334ebb9
DOI: 10.1101/2020.11.23.394270

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Membrane-tethered peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as allosteric biased ligandsDOI 10.1101/2020.11.23.394270Read

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