Article

SARS-CoV-2 variant B.1.1.7 caused HLA-A2 <sup>+</sup> CD8 <sup>+</sup> T cell epitope mutations for impaired cellular immune response

2021-03-29

Abstract excerpt

<h4>SUMMARY</h4> The rapid spreading of the newly emerged SARS-CoV-2 variant, B.1.1.7, highlighted the requirements to better understand adaptive immune responses to this virus. Since CD8 + T cell responses play an important role in disease resolution and modulation in COVID-19 patients, it is essential to address whether these newly emerged mutations would result in altered immune responses. Here we evaluated t...

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Literature Corpus work: 3fdabf3c-8189-5238-8f0b-7b7194102793
DOI: 10.1101/2021.03.28.437363

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