Article

Adrenergic Hypersensitivity Drives Ventricular Arrhythmias Following Loss of Plexin-Mediated Cardiac Innervation

2025-05-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Ventricular arrhythmias (VAs) are a leading cause of death and arise from a combination of cardiac muscle injury and dysfunction of the intramyocardial sympathetic nerves that control cardiac electrophysiology. The adrenergic mechanisms by which intramyocardial nerves contribute to arrhythmogenesis are poorly understood. Semaphorin-plexin signaling pathways are responsible f...

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Literature Corpus work: cf3b0b31-1d56-59d4-bbe3-6cb3e0cf4380
DOI: 10.1101/2025.05.20.655085

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