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Early Metabolic Alterations in Cerebrospinal Fluid Fatty Acid Profiles Linked to Cognitive Decline and All-Cause Dementia

2025-08-30

Abstract excerpt

<h4>Background</h4> While All-cause dementia (ACD) may often be characterized by the abnormal deposition of extracellular β-amyloid (Aβ) in the brain cortex and hyperphosphorylated tau (p-tau) as neurofibrillary tangles intracellularly, there is a need to identify early metabolic changes that may accompany these pathological changes. <h4>Objective</h4> This study evaluated the predictive value of fatty acids in...

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Literature Corpus work
3fa51562-3d33-5a47-a5a8-d6cdc496db39
DOI
10.1101/2025.08.25.672205
Open publication

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Early Metabolic Alterations in Cerebrospinal Fluid Fatty Acid Profiles Linked to Cognitive Decline and All-Cause DementiaDOI 10.1101/2025.08.25.672205
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