Article

Integrating large-scale serum metabolomics and <i>APOE</i> ε4 genotype status for the non-invasive detection of Alzheimer’s disease in the ADNI cohort

2025-12-30

Abstract excerpt

<h4>INTRODUCTION</h4> Accurate Alzheimer’s disease (AD) detection remains challenging and often requires invasive or costly procedures. Blood-based metabolomic signatures offer a promising non-invasive approach. This study aimed to identify a serum metabolite panel and evaluate its performance alone and in combination with apolipoprotein E ( APOE ) ε4 genotype status for distinguishing AD from cognitively norma...

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Literature Corpus work: cabea87a-86ae-50f3-b172-f5699ea433ba
DOI: 10.64898/2025.12.29.25343146

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