Article

SNP analysis implicates role of cytosine methylation in introducing consequential mutations in <i>Vibrio cholerae</i> genomes

2016-08-22

Abstract excerpt

Epigenetic modifications play a key role in gene regulation and in recognition of self DNA in bacteria. In-spite of their positive role in cell survival, modifications like cytosine methylation incur a mutational cost. Cytosine methylation, specifically 5-methylcytosine, is prone to hydrolytic deamination which leads to C → T and G → A transitions. Here, we first study the abundance of mutagenic cytosine methylati...

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Literature Corpus work: 3f9dc927-6d80-534b-9a79-3bb59841a070
DOI: 10.1101/070839

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