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A combination of metagenomic and cultivation approaches reveals hypermutator phenotypes within <i>Vibrio cholerae</i> infected patients

2020-10-12

Abstract excerpt

<h4>ABSTRACT</h4> Vibrio cholerae can cause a range of symptoms, ranging from severe diarrhea to asymptomatic infection. Previous studies using whole genome sequencing (WGS) of multiple bacterial isolates per patient showed that V. cholerae can evolve modest genetic diversity during symptomatic infection. To further explore the extent of V. cholerae within-host diversity, we applied culture-based WGS and metage...

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Literature Corpus work
5aed97ab-b8c2-50a4-91b3-1b26d62ce1d0
DOI
10.1101/2020.10.11.333682
Open publication

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A combination of metagenomic and cultivation approaches reveals hypermutator phenotypes within <i>Vibrio cholerae</i> infected patientsDOI 10.1101/2020.10.11.333682
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