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A <i>Vibrio cholerae</i> Type IV restriction system targets glucosylated 5-hydroxyl methyl cytosine to protect against phage infection

2024-04-05

Abstract excerpt

A major challenge faced by Vibrio cholerae is constant predation by bacteriophage (phage) in aquatic reservoirs and during infection of human hosts. To overcome phage predation, V. cholerae has evolved a myriad of phage defense systems. Although several novel defense systems have been discovered, we hypothesized more were encoded in V. cholerae given the relative paucity of phage that have been isolated which i...

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Literature Corpus work
64b9d21c-13fa-5ee4-b303-4ca1c0093f27
DOI
10.1101/2024.04.05.588314
Open publication

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A <i>Vibrio cholerae</i> Type IV restriction system targets glucosylated 5-hydroxyl methyl cytosine to protect against phage infectionDOI 10.1101/2024.04.05.588314
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