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Exome Sequencing of a Blastomycosis Case-Control Cohort From Manitoba and Northwestern Ontario, Canada.

Mycoses - 1 Sept 2024

Jankowski Paul, Lee Emma R, Embil John, Keynan Yoav, McLaren Paul J

Abstract excerpt

BACKGROUND: Blastomycosis is a pulmonary disease caused by Blastomyces spp., a group of pathogenic dimorphic fungi endemic to a number of geographic regions, specifically Manitoba and northwestern Ontario, Canada. Immunosuppression is a major risk factor affecting disease susceptibility, yet host immunity is not well understood. Genetic immunodeficiencies can also influence disease, with variants in IL6, GATA2...

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PMID: 39307841
DOI: 10.1111/myc.13800

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