Article

Placental-brain axis in females detected within broadly impacted metabolic gene networks protects against prenatal PCB exposure

2024-07-17

Abstract excerpt

<h4>Background</h4> Neurodevelopmental disorders have a strong male bias that is poorly understood. Placenta is a rich source of molecular information about environmental interactions with genetics (including biological sex), that affect the developing brain. We investigated placental-brain transcriptional responses in an established mouse model of prenatal exposure to a human-relevant mixture of polychlorinated...

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Literature Corpus work: 3f154807-0f98-5270-8c4f-bcb33d9a45c6
DOI: 10.1101/2024.07.14.603326

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