Article

SUMOylation Inhibition Enhances Dexamethasone Sensitivity in Multiple Myeloma

2021-08-13

Abstract excerpt

<title>Abstract</title> <p>BackgroundMultiple myeloma (MM) is an incurable plasma cell malignancy. Although Dexamethasone (Dex) is the most widely used therapeutic drug in MM treatment, patients develop Dex resistance leading to progressive disease, demanding an urgent need to investigate the mechanisms driving Dex resistance and develop new reagents to address this problem. We propose SUMOylation as a potential...

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Literature Corpus work: 3f5a0e5a-3922-53da-bc8c-062c08393b7f
DOI: 10.21203/rs.3.rs-786759/v1

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