Article
The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome.
Blood - 8 Apr 2010
Driscoll James J, Pelluru Dheeraj, Lefkimmiatis Konstantinos, Fulciniti Mariateresa, Prabhala Rao H, Greipp Philip R, Barlogie Bart, Tai Yu-Tzu, Anderson Kenneth C, Shaughnessy John D, Annunziata Christina M, Munshi Nikhil C
Abstract excerpt
Multiple myeloma (MM) is a plasma cell neoplasm that proceeds through a premalignant state of monoclonal gammopathy of unknown significance; however, the molecular events responsible for myelomagenesis remain uncharacterized. To identify cellular pathways deregulated in MM, we addressed that sumo...
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