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Article

LncRNA NEAT1 promotes dexamethasone resistance in multiple myeloma by targeting miR-193a/MCL1 pathway.

Journal of biochemical and molecular toxicology - 1 Jan 2018

Wu Yilan, Wang Han

Abstract excerpt

Although dexamethasone (DEX) remains a first-line agent for multiple myeloma (MM) therapy, the development of DEX resistance has become an indicator of poor prognosis in MM patients. It is thus urgent to develop strategies to restore the vulnerability of MM to DEX. This study demonstrated long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1) was highly expressed in DEX-resistant myeloma...

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Share to Antineoplastic Agents, Hormonal
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Share to Multiple Myeloma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myeloid Cell Leukemia Sequence 1 Protein

Share to RNA, Long Noncoding

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Source

Identifiers

PMID: 29205703
DOI: 10.1002/jbt.22008

Genes

MCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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