Article

New characterization and safety evaluation of human limbal stem cells used in clinical application: fidelity of mitotic process and mitotic spindle morphologies

2023-08-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Limbal stem cells(LSCs) are crucial for the regeneration of the corneal epithelium in patients with limbal stem cell deficiency (LSCD). Thus, LSCs during cultivation <italic>in vitro</italic> should be in highly homogeneous amounts, while potency and expression of stemness without tumorigenesis would be desirable. Therefore, further characterization and safety ev...

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Literature Corpus work: 3f134f2a-ceaa-55a5-b968-d0cb76698459
DOI: 10.21203/rs.3.rs-3239976/v1

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