Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge

4 Oct 2023

Abstract excerpt

Mpox virus (MPXV) caused a global outbreak in 2022. Although smallpox vaccines were rapidly deployed to curb spread and disease among those at highest risk, breakthrough disease was noted after complete immunization. Given the threat of additional zoonotic events and the virus’s evolving ability to drive human-to-human transmission, there is an urgent need for an MPXV-specific vaccine that confers protection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Immunotherapy and Immune Responses
Share to Poxvirus research and outbreaks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37792954
DOI: 10.1126/scitranslmed.adg3540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challengePMID 37792954Read ↗

A monkeypox mRNA-lipid nanoparticle vaccine targeting virus binding, entry, and transmission drives protection against lethal orthopoxviral challengeSemantic proximity Read ↗

Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primatesSemantic proximity Read ↗

Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primatesSemantic proximity Read ↗

A multivalent mRNA vaccine elicits robust immune responses and confers protection in a murine model of monkeypox virus infectionSemantic proximity Read ↗

Polyvalent mRNA vaccination elicited potent immune response to monkeypox surface antigensSemantic proximity Read ↗

Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2Semantic proximity Read ↗

A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus diseaseSemantic proximity Read ↗

Comprehensive Profiling of Monkeypox Virus Antigens Identifies Potent Targets for Next-Generation mRNA Vaccine DevelopmentSemantic proximity Read ↗

The unique immune evasion mechanisms of the mpox virus and their implication for developing new vaccines and immunotherapiesSemantic proximity Read ↗

A mRNA-LNP vaccine against Dengue Virus elicits robust, serotype-specific immunitySemantic proximity Read ↗

An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infectionSemantic proximity Read ↗

Mpox vaccine and infection-driven human immune signaturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.