Article

Investigating the Relationship Between Gut Microbiota and Ischemic Stroke: Genetic Causality and Metabolite Mediation

2024-07-15

Abstract excerpt

<title>Abstract</title> <p>Background The gut microbiota(GM) plays a significant role in health and disease, with numerous studies confirming its association with various diseases. This study aims to evaluate the genetic causal relationship between GM and ischemic stroke (IS), along with exploring potential blood metabolite-mediated mechanisms. Methods Utilizing two-sample Mendelian Randomization (MR) and large...

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Literature Corpus work: 3ee4cb15-e1fc-590f-badf-8b6e534f61f8
DOI: 10.21203/rs.3.rs-4341342/v1

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