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Article

Gut metabolites and functional recovery after ischemic stroke: a genetic perspective.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2025

Wu Wenpeng, Zhu Luwen, Zhang Jiongliang, Li Xinyue, Yu Donghui, Wang Yuting, Su Yumeng, Wei Xiangyu, Ma Hanwen, Song Wenjing, Li Jinting, Teng Lili, Tang Qiang, Wu Minmin

Abstract excerpt

The current study explores the relationship between genetically predicted gut metabolites and functional outcomes following ischemic stroke, utilizing the Mendelian Randomization (MR) framework. Genetic information regarding gut microbiota-derived metabolites was sourced from 2076 participants of European descent participating in the Framingham Heart Study. Data on functional outcomes 90 days post-ischemic stroke...

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PMID: 40056206
DOI: 10.1007/s00335-025-10120-4

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