Article
Causal Link Between Gut Microbiota and Arterial Occlusive Diseases: Insights From Mendelian Randomization and Bioinformatics Analysis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions - 1 Oct 2025
Lin Xin, Xu Kangdi
Abstract excerpt
BACKGROUND: Arterial occlusive diseases (AOD), including peripheral artery disease (PAD), are significant causes of morbidity and mortality worldwide. Emerging evidence suggests that gut microbiota may play a crucial role in the pathogenesis of PAD. However, causal relationships remain unclear due to limitations in observational studies. AIMS: This study aims to investigate the causal relationship between gut...
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