Article

Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury

2024-03-19

Abstract excerpt

COVID-19 has been a significant public health concern for the last four years; however, little is known about the mechanisms that lead to severe COVID-associated kidney injury. In this multicenter study, we combined quantitative deep urinary proteomics and machine learning to predict severe acute outcomes in hospitalized COVID-19 patients. Using a 10-fold cross-validated random forest algorithm, we identified a se...

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Literature Corpus work: 3ee14f52-ed27-58c9-a917-14a8a179f8d7
DOI: 10.1101/2024.03.18.24304401

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