Article

Spatiotemporal Gray Matter Plasticity During Chronification of Preclinical Neuropathic Pain

2025-10-04

Abstract excerpt

Chronic neuropathic pain is increasingly recognized as a brain disease characterized by time-dependent structural and functional reorganization of key neural circuits. While human imaging studies implicate widespread changes in network connectivity and gray matter density (GMD), animal models enable direct longitudinal mapping of such plasticity. Here, we applied high-resolution structural MRI in a rat model of ch...

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Literature Corpus work: 3ece9e5e-d47a-5326-82f1-d58a8061784a
DOI: 10.1101/2025.10.03.679890

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