Article

Transcriptional Correlates of Structure-Function Coupling Plasticity in Trigeminal Neuralgia: Unveiling the Synaptic and Metabolic Mechanisms of Recovery

2026-01-08

Abstract excerpt

<title>Abstract</title> <p>Background Trigeminal neuralgia (TN) is a neurological disorder characterised by severe facial pain and is a common cause of orofacial headache. While vascular compression is a known peripheral trigger, the condition involves a transition to central sensitization. However, the core central pathophysiological mechanisms—particularly how the brain structurally and functionally reorganise...

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Literature Corpus work: 678029c1-192b-5756-b69f-9d683f4eaab1
DOI: 10.21203/rs.3.rs-8527336/v1

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