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Article

Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: implications for learning and memory.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Jul 2011

Amador-Arjona Alejandro, Elliott Jimmy, Miller Amber, Ginbey Ashley, Pazour Gregory J, Enikolopov Grigori, Roberts Amanda J, Terskikh Alexey V

Abstract excerpt

Integration of new neurons into the adult hippocampus has been linked to specific types of learning. Primary cilia were found to be required for the formation of adult neural stem cells (NSCs) in the hippocampal dentate gyrus during development. However, the requirement of cilia in maintenance of adult NSCs is unknown. We developed a genetic mouse model in which fetal/perinatal brain development is unaffected,...

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Identifiers

PMID: 21734285
DOI: 10.1523/JNEUROSCI.1062-11.2011
PMCID: PMC3758574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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