Article

Iron homeostasis and endometriosis risk: Genetic evidence for a shared biological link

2026-08-28

Abstract excerpt

STUDY QUESTION Is genetic liability to endometriosis associated with iron homeostasis, and is this relationship potentially causal? SUMMARY ANSWER Genetic evidence indicates that reduced systemic iron status is associated with increased risk of endometriosis, with evidence of 8 shared genome-wide significant loci and suggestive but inconsistent evidence for causal bidirectional effects. WHAT IS KNOWN ALREADY End...

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Literature Corpus work: 3e8d3ec9-da9e-5b38-b3ef-b528376bbc97
DOI: 10.64898/2026.08.25.26361232

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