Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between genetic risk and comorbid conditions in endometriosis.

HGG advances - 10 Jul 2025

McGrath Isabelle M, Rukins Valentina, Laisk Triin, Mortlock Sally, Montgomery Grant W

Abstract excerpt

Endometriosis is a complex disease, and many genetic and environmental risk factors contribute to disease risk. The genetic risk of endometriosis has been well characterized in genome-wide association studies. While few physiological risk factors are known, endometriosis is associated with many comorbid disorders. This study examines the interplay between genetic risk factors, comorbid disorders, and...

Read the complete abstract on PubMed

Topics

Humans
Endometriosis
Female
Comorbidity
Genetic Predisposition to Disease
Adult
Risk Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genome-Wide Association Study

Middle Aged

United Kingdom

Prevalence

Estonia

Case-Control Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 40369874
DOI: 10.1016/j.xhgg.2025.100456
PMCID: PMC12159439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between genetic risk and comorbid conditions in endometriosis.PMID 40369874Read ↗

Genomic characterisation of the overlap of endometriosis with 76 comorbidities identifies pleiotropic and causal mechanisms underlying disease risk.Semantic proximity Read ↗

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditionsSemantic proximity Read ↗

Evidence of shared genetic factors in the aetiology of gastrointestinal disorders and endometriosis and clinical implications for disease managementSemantic proximity Read ↗

The burden of endometriosis on quality of life in Danish blood donorsSemantic proximity Read ↗

Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity.Semantic proximity Read ↗

Genetic liability for endometriosis associates with pain, inflammatory, and metabolic traits: a polygenic score analysisSemantic proximity Read ↗

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions.Semantic proximity Read ↗

Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosteroneSemantic proximity Read ↗

Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations.Semantic proximity Read ↗

Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health recordsSemantic proximity Read ↗

The phenotypic and genetic association between endometriosis and immunological diseasesSemantic proximity Read ↗

Multi-ancestry genome-wide association study of endometriosis and its clinical manifestations in ~1.4 million women: translating gene discovery into pathogenic mechanisms and therapeutic targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.