Article

Multi-ancestry genome-wide association study of endometriosis and its clinical manifestations in ~1.4 million women: translating gene discovery into pathogenic mechanisms and therapeutic targets

2025-09-05

Abstract excerpt

We conducted a multi-ancestry genome-wide association study of endometriosis and adenomyosis in almost 1.4 million women, including 105,869 cases, aiming to expand endometriosis loci discovery across ancestries, dissect symptom-specific effects, and integrate multi-omic data. We identified 80 genome-wide significant associations, 37 of which are novel, including five loci that are the first ever variants reported...

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Literature Corpus work: 0d01323f-0839-58ca-b004-0a4c6388a01f
DOI: 10.1101/2025.09.03.25335012

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