Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without Adaptation

24 Sept 2019

Abstract excerpt

Lassa virus, the causative agent of Lassa fever, is a zoonotic pathogen causing annual outbreaks in West African countries. Human patients can develop lethal hemorrhagic fever in severe cases. Although Lassa virus is one of the most alarming pathogens from a public health perspective, there are few available countermeasures, such as antiviral drugs or vaccines. Moreover, the fact that animal models are not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacillus and Francisella bacterial research
Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31554720
DOI: 10.1128/msphere.00428-19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without AdaptationPMID 31554720Read ↗

Identification of Factors Contributing to Pathogenic Variability Among Lassa Virus Strains Using the Guinea Pig Model and Reverse GeneticsSemantic proximity Read ↗

Unraveling factors responsible for pathogenic differences in Lassa virus strainsSemantic proximity Read ↗

Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developmentsSemantic proximity Read ↗

A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigsSemantic proximity Read ↗

Characterization of a novel intratracheal aerosol challenge model of <i>Brucella melitensis</i> in guinea pigsSemantic proximity Read ↗

Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4bSemantic proximity Read ↗

Lassa Fever: Critical Review and Prospects for ControlSemantic proximity Read ↗

A Recently Isolated Lassa Virus From Mali Demonstrates Atypical Clinical Disease Manifestations and Decreased Virulence in Cynomolgus MacaquesSemantic proximity Read ↗

Development of Infectious Clones for Virulent and Avirulent Pichinde Viruses: a Model Virus To Study Arenavirus-Induced Hemorrhagic FeversSemantic proximity Read ↗

Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicitySemantic proximity Read ↗

Intramuscular Inoculation of Pigs with Foot-and-Mouth Disease Virus is a Practical Alternative to Intradermal Injection into the Heel BulbSemantic proximity Read ↗

Pathological lesions and presence of viral antigens in four surviving pigs in African swine fever outbreak farms in Vietnam.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.