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Article

Mouse Model of Coxiella burnetii Aerosolization.

Infection and immunity - 1 Jul 2016

Melenotte Cléa, Lepidi Hubert, Nappez Claude, Bechah Yassina, Audoly Gilles, Terras Jérôme, Raoult Didier, Brégeon Fabienne

Abstract excerpt

Coxiella burnetii is mainly transmitted by aerosols and is responsible for multiple-organ lesions. Animal models have shown C. burnetii pathogenicity, but long-term outcomes still need to be clarified. We used a whole-body aerosol inhalation exposure system to mimic the natural route of infection in immunocompetent (BALB/c) and severe combined immunodeficient (SCID) mice. After an initial lung inoculum of 10(4)...

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Identifiers

PMID: 27160294
DOI: 10.1128/IAI.00108-16
PMCID: PMC4936361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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