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Murine Aerosol Challenge Model of Anthrax

13 Mar 2007

Abstract excerpt

The availability of relevant and useful animal models is critical for progress in the development of effective vaccines and therapeutics. The infection of rabbits and non-human primates with fully virulent Bacillus anthracis spores provides two excellent models of anthrax disease. However, the high cost of procuring and housing these animals and the specialized facilities required to deliver fully virulent spores...

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PMID: 17353290
DOI: 10.1128/iai.01875-06

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