Article

Models of neurodegeneration using computational approaches

2016-01-01

Abstract excerpt

Alzheimer's disease (AD), as one of the most common neurodegenerative diseases, is characterized by the loss of neuronal dysfunction and death resulting in progressive cognitive impairment. The main histopathological hallmark of AD is the accumulation and deposition of misfolded Aβ peptide as amyloid plaques, however the precise role of Aβ toxicity in the disease pathogenesis is still unclear. Moreover, at early s...

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Literature Corpus work: 3df35295-c43e-59a1-93b1-7586a414abc0
DOI: 10.17863/cam.21242

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