Article
Impact of Zygosity in Bimodal Phenotype Distributions
2016-11-09
Abstract excerpt
Allele number, or zygosity, is a clear determinant of gene expression in diploid cells. But the relationship between the number of copies of a gene and its expression can be hard to anticipate, especially when the gene in question is embedded in a regulatory circuit that contains feedbacks. Here we study this question making use of the natural genetic variability of human populations, which allows us to compare th...
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Identifiers and source
- Literature Corpus work
- 3ddda963-b274-53d4-a207-5622e290384b
- DOI
- 10.1101/086215