Article

Fast and Accurate Genomic Analyses using Genome Graphs

2017-09-27

Abstract excerpt

The human reference genome serves as the foundation for genomics by providing a scaffold for alignment of sequencing reads, but currently only reflects a single consensus haplotype, which impairs read alignment and downstream analysis accuracy. Reference genome structures incorporating known genetic variation have been shown to improve the accuracy of genomic analyses, but have so far remained computationally proh...

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Literature Corpus work: 3dcfe3fa-da35-5c81-a173-357e631eb4bf
DOI: 10.1101/194530

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