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Glucose clearance and uptake is increased in the SOD1 <sub>G93A</sub> mouse model of amyotrophic lateral sclerosis through an insulin-independent mechanism

2020-08-03

Abstract excerpt

Metabolic disturbances are associated with the progression of the neurodegenerative disorder, amyotrophic lateral sclerosis (ALS), however the molecular events that drive energy imbalances in ALS are not completely understood. In this study we aimed to elucidate deficits in energy homeostasis in the SOD1 G93A mouse model of ALS. We identified that SOD1 G93A mice at mid-symptomatic disease stage have increased ox...

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Literature Corpus work
3dc283ca-7135-5a87-b694-3361576d23bf
DOI
10.1101/2020.08.02.233411
Open publication

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Glucose clearance and uptake is increased in the SOD1 <sub>G93A</sub> mouse model of amyotrophic lateral sclerosis through an insulin-independent mechanismDOI 10.1101/2020.08.02.233411
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