Article

HINS: HLA-mediated immunogenic neoantigen score for robust prediction of immune checkpoint blockade response

2025-12-12

Abstract excerpt

Immune checkpoint blockade (ICB) therapy response prediction provides remarkable genomic and transcriptomic gains and has successfully understood the molecular mechanisms underlying various cancers. However, only a subset of patients with advanced tumors currently benefits from ICB therapies, which at times incur considerable side effects and costs. Developing predictive tools for ICB response has remained a serio...

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Literature Corpus work: 3d64bde8-a6fa-54e8-b438-c41fb4053013
DOI: 10.64898/2025.12.09.693330

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